The resulting crater blocks the entrance to the Architect cache and the impact toppled one of the cache's pillars. A meteorite strikes 4546B in the Dunes biome.It is believed the Architects also discovered the Gargantuan Fossil around this time and began to take samples from its rib cage. The Architects construct the Quarantine Enforcement Platform, Disease Research Facility, Alien Thermal Plant, and Sanctuary Caches and began constructing Warpers (whether this was the first time Warpers were constructed is unknown). The Architects quarantined their core worlds and brought Kharaa to isolated disease research facilities, including on Planet 4546B, in order to research and develop a cure. A network error caused the Architects' routine quarantine procedure to fail, resulting in at least 143 billion deaths on their core worlds. The Architects discover the Kharaa Bacterium on an outer planet during a routine network expansion.At some point, Earth dolphins become extinct.
